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  1. DNA microarray analysis has been used for the first time to define clinically relevant subtypes of lymphoma.

    Authors: Jonathan B Weitzman
    Citation: Genome Biology 2000 1:reports0042
  2. The nucleotide sequence of the 120 megabase euchromatic region of the Drosophila melanogaster genome is reported.

    Authors: Alan Shirras
    Citation: Genome Biology 2000 1:reports038
  3. Transcriptional analysis has been used to probe the biology of mycobacterial responses to antibiotics and to suggest new drug targets.

    Authors: Zachary Perlman
    Citation: Genome Biology 2000 1:reports037
  4. Expression patterns of Vibrio cholerae virulence genes determined during an infection differ dramatically from those observed in conventional in vitro analyses.

    Authors: William Deakin
    Citation: Genome Biology 2000 1:reports036
  5. A new technique for the selection of newly synthesized DNA has enabled the selection and amplification of putative origins of replication on the human X chromosome.

    Authors: Shuba Gopal
    Citation: Genome Biology 2000 1:reports035
  6. A report from the "Quantitative challenges in the post-genomic sequence era" workshop and symposium, San Diego, January 11-15, 2000

    Authors: Gregory A Petsko
    Citation: Genome Biology 2000 1:reports406.1
  7. A report from the minisymposium on regulated secretion at the 39th Annual Meeting of the American Society for Cell Bilogy, Washington DC, December 11-15, 1999

    Authors: Colin Jamora
    Citation: Genome Biology 2000 1:reports402.1
  8. Launched in September 1998, dbSNP is the central repository for data on single-nucleotide polymorphisms (SNPs), the most common form of sequence variation in human populations.

    Authors: Colin Semple
    Citation: Genome Biology 2000 1:reports243
  9. Given the variety of codon usage by different organisms and organelles, this centralized codon-usage resource is invaluable.

    Authors: Todd Richmond
    Citation: Genome Biology 2000 1:reports241
  10. The unified database (UDB) attempts to create an integrated map based on human genome mapping data retrieved from a number of public databases.

    Authors: Kathryn Evans
    Citation: Genome Biology 2000 1:reports238
  11. Finding the relevant database is not always easy, and for some years Nucleic Acids Research has dedicated its first issue of the year to information about the most important existing databases.

    Authors: Mar Albà
    Citation: Genome Biology 2000 1:reports235
  12. For those working on the actin cytoskeleton, a major theme of the 39th annual meeting of the American Society for Cell Biology [

    Authors: Anne Ridley
    Citation: Genome Biology 2000 1:reviews102.1
  13. GeneCalling, a new expression profiling technique, has been used to elucidate regulatory gene networks in plants.

    Authors: Leonore Reiser
    Citation: Genome Biology 2000 1:reports034
  14. Members of the Arabidopsis Genome Initiative, including the European Union Arabidopsis Genome Sequencing Consortium and The Cold Spring Harbor, Washington University in St Louis and PE Biosystems Arabidopsis Sequ...

    Authors: Todd Richmond
    Citation: Genome Biology 2000 1:reports030
  15. Mouse chromosomes carrying deletions have been produced using a combination of targeted and random integration of selectable markers followed by specific excision by a recombinase.

    Authors: Paul Denny
    Citation: Genome Biology 2000 1:reports027
  16. PCR screening five collections of mutagenized Arabidopsis lines to find those that have T-DNA or transposon insertions in 73 members of the R2R3 MYB gene family has identified 47 insertions into 36 genes.

    Authors: Seung Yon Rhee
    Citation: Genome Biology 2000 1:reports025
  17. A new noninvasive technique has been developed that successfully measures calcium dynamics in single Arabidopsis guard cells.

    Authors: Kath Carr and Alistair Hetherington
    Citation: Genome Biology 2000 1:reports024
  18. The crystal structure of human SRP54M from the signal recognition particle (SRP) reveals a homodimer interaction, which may be a model for the way signal sequences on nascent proteins recognize and activate th...

    Authors: Rachel Brem
    Citation: Genome Biology 2000 1:reports020
  19. Correlation-based clustering of plant expressed sequence tags allows conclusions to be drawn about the relationship between genes based on their expression patterns in different tissues.

    Authors: Philippe Reymond
    Citation: Genome Biology 2000 1:reports010

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