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Featured article: CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops

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Content type: Method
| 22 October 2018

SCoPE-MS: mass spectrometry of single mammalian cells quantifies proteome heterogeneity during cell differentiation

Authors: Bogdan Budnik, Ezra Levy, Guillaume Harmange and Nikolai Slavov
Content type: Research
| 19 October 2018

Harnessing accurate non-homologous end joining for efficient precise deletion in CRISPR/Cas9-mediated genome editing

Authors: Tao Guo, Yi-Li Feng, Jing-Jing Xiao, Qian Liu, Xiu-Na Sun, Ji-Feng Xiang, Na Kong, Si-Cheng Liu, Guo-Qiao Chen, Yue Wang, Meng-Meng Dong, Zhen Cai, Hui Lin, Xiu-Jun Cai and An-Yong Xie
Content type: Method
| 19 October 2018

SeqOthello: querying RNA-seq experiments at scale

Authors: Ye Yu, Jinpeng Liu, Xinan Liu, Yi Zhang, Eamonn Magner, Erik Lehnert, Chen Qian and Jinze Liu
Content type: Method
| 19 October 2018

CRISPRO: identification of functional protein coding sequences based on genome editing dense mutagenesis

Authors: Vivien A. C. Schoonenberg, Mitchel A. Cole, Qiuming Yao, Claudio Macias-Treviño, Falak Sher, Patrick G. Schupp, Matthew C. Canver, Takahiro Maeda, Luca Pinello and Daniel E. Bauer
Content type: Research
| 19 October 2018

Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial

Authors: Emma E. Davenport, Tiffany Amariuta, Maria Gutierrez-Arcelus, Kamil Slowikowski, Harm-Jan Westra, Yang Luo, Ciyue Shen, Deepak A. Rao, Ying Zhang, Stephen Pearson, David von Schack, Jean S. Beebe, Nan Bing, Sally John, Michael S. Vincent, Baohong Zhang…

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Content type: Comment
| 30 July 2014

The Kardashian index: a measure of discrepant social media profile for scientists

Authors: Neil Hall
Content type: Review
| 26 January 2016

A survey of best practices for RNA-seq data analysis

Authors: Ana Conesa, Pedro Madrigal, Sonia Tarazona, David Gomez-Cabrero, Alejandra Cervera, Andrew McPherson, Michał Wojciech Szcześniak, Daniel J. Gaffney, Laura L. Elo, Xuegong Zhang and Ali Mortazavi

The Erratum to this article has been published in Genome Biology 2016 17:181
Content type: Method
| 27 October 2010

Differential expression analysis for sequence count data

Authors: Simon Anders and Wolfgang Huber
Content type: METHOD
| 5 December 2014

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Authors: Michael I Love, Wolfgang Huber and Simon Anders
Content type: Research
| 10 December 2013

DNA methylation age of human tissues and cell types

Authors: Steve Horvath

The Erratum to this article has been published in Genome Biology 2015 16:96

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Genome Biology

Call for Papers: Microbiome Biology

Featured article: CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops

Articles

SCoPE-MS: mass spectrometry of single mammalian cells quantifies proteome heterogeneity during cell differentiation

Harnessing accurate non-homologous end joining for efficient precise deletion in CRISPR/Cas9-mediated genome editing

SeqOthello: querying RNA-seq experiments at scale

CRISPRO: identification of functional protein coding sequences based on genome editing dense mutagenesis

Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial

The Kardashian index: a measure of discrepant social media profile for scientists

A survey of best practices for RNA-seq data analysis

Differential expression analysis for sequence count data

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

DNA methylation age of human tissues and cell types

Latest articles from Genome Medicine

Genotype effects contribute to variation in longitudinal methylome patterns in older people

T cell dynamics and response of the microbiota after gene therapy to treat X-linked severe combined immunodeficiency

Clinical exome sequencing for fetuses with ultrasound abnormalities and a suspected Mendelian disorder

Focus: the Microbiome

Reviews, Research highlights and commentaries

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From the blog

Aging and the intricacies of the immune system

Best of 2017: Top Picks from Genome Biology

Living in an RNA world

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