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Open chromatin interaction maps reveal functional regulatory elements and chromatin architecture variations during wheat evolution

Authors: Jingya Yuan, Haojie Sun, Yijin Wang, Lulu Li, Shiting Chen, Wu Jiao, Guanghong Jia, Longfei Wang, Junrong Mao, Zhongfu Ni, Xiue Wang and Qingxin Song

Content type: Research

24 January 2022
IDEAS: individual level differential expression analysis for single-cell RNA-seq data

Authors: Mengqi Zhang, Si Liu, Zhen Miao, Fang Han, Raphael Gottardo and Wei Sun

Content type: Method

24 January 2022
sPLINK: a hybrid federated tool as a robust alternative to meta-analysis in genome-wide association studies

Authors: Reza Nasirigerdeh, Reihaneh Torkzadehmahani, Julian Matschinske, Tobias Frisch, Markus List, Julian Späth, Stefan Weiss, Uwe Völker, Esa Pitkänen, Dominik Heider, Nina Kerstin Wenke, Georgios Kaissis, Daniel Rueckert, Tim Kacprowski and Jan Baumbach

Content type: Method

24 January 2022
Nanopore adaptive sampling: a tool for enrichment of low abundance species in metagenomic samples

Authors: Samuel Martin, Darren Heavens, Yuxuan Lan, Samuel Horsfield, Matthew D. Clark and Richard M. Leggett

Content type: Method

24 January 2022
Statistics or biology: the zero-inflation controversy about scRNA-seq data

Authors: Ruochen Jiang, Tianyi Sun, Dongyuan Song and Jingyi Jessica Li

Content type: Review

21 January 2022

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The Kardashian index: a measure of discrepant social media profile for scientists

Authors: Neil Hall

Content type: Comment

30 July 2014
A survey of best practices for RNA-seq data analysis

Authors: Ana Conesa, Pedro Madrigal, Sonia Tarazona, David Gomez-Cabrero, Alejandra Cervera, Andrew McPherson, Michał Wojciech Szcześniak, Daniel J. Gaffney, Laura L. Elo, Xuegong Zhang and Ali Mortazavi

Content type: Review

26 January 2016

The Erratum to this article has been published in Genome Biology 2016 17:181
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Authors: Jo Vandesompele, Katleen De Preter, Filip Pattyn, Bruce Poppe, Nadine Van Roy, Anne De Paepe and Frank Speleman

Content type: Research

18 June 2002
Differential expression analysis for sequence count data

Authors: Simon Anders and Wolfgang Huber

Content type: Method

27 October 2010
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Authors: Michael I Love, Wolfgang Huber and Simon Anders

Content type: METHOD

5 December 2014

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Latest articles from Genome Medicine

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Cisplatin and carboplatin result in similar gonadotoxicity in immature human testis with implications for fertility preservation in childhood cancer
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Large-scale discovery of male reproductive tract-specific genes through analysis of RNA-seq datasets
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DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies
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Published in Genome Medicine 25 November 2020

The Tug1 lncRNA locus is essential for male fertility
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Published in Genome Biology 07 September 2020

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Reviewer Acknowledgements 2020

The Editors and staff of Genome Biology would like to warmly thank the Reviewers whose comments helped to shape the journal, for their invaluable assistance with review of manuscripts in 2020.

Genome Biology

Special Issue: Long Read Sequencing

Call for Papers: Interpretable Deep Learning Special Issue

Articles

Open chromatin interaction maps reveal functional regulatory elements and chromatin architecture variations during wheat evolution

IDEAS: individual level differential expression analysis for single-cell RNA-seq data

sPLINK: a hybrid federated tool as a robust alternative to meta-analysis in genome-wide association studies

Nanopore adaptive sampling: a tool for enrichment of low abundance species in metagenomic samples

Statistics or biology: the zero-inflation controversy about scRNA-seq data

The Kardashian index: a measure of discrepant social media profile for scientists

A survey of best practices for RNA-seq data analysis

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Differential expression analysis for sequence count data

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Latest articles from Genome Medicine

Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1

ClinGen Variant Curation Interface: a variant classification platform for the application of evidence criteria from ACMG/AMP guidelines

A lepidic gene signature predicts patient prognosis and sensitivity to immunotherapy in lung adenocarcinoma

Focus: Fertility

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Exploring the history of smallpox vaccination with 19th Century American vaccination kits

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