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Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents

Authors: Ádám Póti, Hella Gyergyák, Eszter Németh, Orsolya Rusz, Szilárd Tóth, Csenger Kovácsházi, Dan Chen, Bernadett Szikriszt, Sándor Spisák, Shunichi Takeda, Gergely Szakács, Zoltan Szallasi, Andrea L. Richardson and Dávid Szüts

Content type: Research

14 November 2019
NanoSatellite: accurate characterization of expanded tandem repeat length and sequence through whole genome long-read sequencing on PromethION

Authors: Arne De Roeck, Wouter De Coster, Liene Bossaerts, Rita Cacace, Tim De Pooter, Jasper Van Dongen, Svenn D’Hert, Peter De Rijk, Mojca Strazisar, Christine Van Broeckhoven and Kristel Sleegers

Content type: Method

14 November 2019
OrthoFinder: phylogenetic orthology inference for comparative genomics

Authors: David M. Emms and Steven Kelly

Content type: Software

14 November 2019
Differential co-expression-based detection of conditional relationships in transcriptional data: comparative analysis and application to breast cancer

Authors: Dharmesh D. Bhuva, Joseph Cursons, Gordon K. Smyth and Melissa J. Davis

Content type: Research

14 November 2019
Evaluation of commonly used analysis strategies for epigenome- and transcriptome-wide association studies through replication of large-scale population studies

Authors: Jeroen van Rooij, Pooja R. Mandaviya, Annique Claringbould, Janine F. Felix, Jenny van Dongen, Rick Jansen, Lude Franke, Peter A. C. ’t Hoen, Bas Heijmans and Joyce B. J. van Meurs

Content type: Research

14 November 2019

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The Kardashian index: a measure of discrepant social media profile for scientists

Authors: Neil Hall

Content type: Comment

30 July 2014
A survey of best practices for RNA-seq data analysis

Authors: Ana Conesa, Pedro Madrigal, Sonia Tarazona, David Gomez-Cabrero, Alejandra Cervera, Andrew McPherson, Michał Wojciech Szcześniak, Daniel J. Gaffney, Laura L. Elo, Xuegong Zhang and Ali Mortazavi

Content type: Review

26 January 2016

The Erratum to this article has been published in Genome Biology 2016 17:181
Differential expression analysis for sequence count data

Authors: Simon Anders and Wolfgang Huber

Content type: Method

27 October 2010
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Authors: Michael I Love, Wolfgang Huber and Simon Anders

Content type: METHOD

5 December 2014
DNA methylation age of human tissues and cell types

Authors: Steve Horvath

Content type: Research

10 December 2013

The Erratum to this article has been published in Genome Biology 2015 16:96

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Genome Biology

Benchmarking Studies

Featured article:RNA expression and alternative splicing in advanced age

Articles

Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents

NanoSatellite: accurate characterization of expanded tandem repeat length and sequence through whole genome long-read sequencing on PromethION

OrthoFinder: phylogenetic orthology inference for comparative genomics

Differential co-expression-based detection of conditional relationships in transcriptional data: comparative analysis and application to breast cancer

Evaluation of commonly used analysis strategies for epigenome- and transcriptome-wide association studies through replication of large-scale population studies

The Kardashian index: a measure of discrepant social media profile for scientists

A survey of best practices for RNA-seq data analysis

Differential expression analysis for sequence count data

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

DNA methylation age of human tissues and cell types

Latest articles from Genome Medicine

From cytogenetics to cytogenomics: whole-genome sequencing as a first-line test comprehensively captures the diverse spectrum of disease-causing genetic variation underlying intellectual disability

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Inflammatory cytokines and organ dysfunction associate with the aberrant DNA methylome of monocytes in sepsis

Focus: Complex Data Analysis in Health and Disease

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The fascination of plant genomes

Genome Biology at Genome Informatics

Bigger CRISPR- Cas12a toolbox, wider genomic coverage and higher targeting efficiencies

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