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BindVAE: Dirichlet variational autoencoders for de novo motif discovery from accessible chromatin

Authors: Meghana Kshirsagar, Han Yuan, Juan Lavista Ferres and Christina Leslie

Content type: Method 15 August 2022
Single-cell diploid Hi-C reveals the role of spatial aggregations in complex rearrangements and KMT2A fusions in leukemia

Authors: Zhihao Xing, Huirong Mai, Xiaorong Liu, Xiaoying Fu, Xingliang Zhang, Lichun Xie, Yunsheng Chen, Adam Shlien and Feiqiu Wen

Content type: Research 9 August 2022
The recombination landscape of the Khoe-San likely represents the upper limits of recombination divergence in humans

Authors: Gerald van Eeden, Caitlin Uren, Evlyn Pless, Mira Mastoras, Gian D. van der Spuy, Gerard Tromp, Brenna M. Henn and Marlo Möller

Content type: Research 9 August 2022
A benchmark study of deep learning-based multi-omics data fusion methods for cancer

Authors: Dongjin Leng, Linyi Zheng, Yuqi Wen, Yunhao Zhang, Lianlian Wu, Jing Wang, Meihong Wang, Zhongnan Zhang, Song He and Xiaochen Bo

Content type: Research 9 August 2022
Balanced mitochondrial and cytosolic translatomes underlie the biogenesis of human respiratory complexes

Authors: Iliana Soto, Mary Couvillion, Katja G. Hansen, Erik McShane, J. Conor Moran, Antoni Barrientos and L. Stirling Churchman

Content type: Research 9 August 2022

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The Kardashian index: a measure of discrepant social media profile for scientists

Authors: Neil Hall

Content type: Comment 30 July 2014
A survey of best practices for RNA-seq data analysis

Authors: Ana Conesa, Pedro Madrigal, Sonia Tarazona, David Gomez-Cabrero, Alejandra Cervera, Andrew McPherson, Michał Wojciech Szcześniak, Daniel J. Gaffney, Laura L. Elo, Xuegong Zhang and Ali Mortazavi

Content type: Review 26 January 2016

The Erratum to this article has been published in Genome Biology 2016 17:181
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Authors: Jo Vandesompele, Katleen De Preter, Filip Pattyn, Bruce Poppe, Nadine Van Roy, Anne De Paepe and Frank Speleman

Content type: Research 18 June 2002
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Authors: Michael I Love, Wolfgang Huber and Simon Anders

Content type: METHOD 5 December 2014
Differential expression analysis for sequence count data

Authors: Simon Anders and Wolfgang Huber

Content type: Method 27 October 2010

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Genome Biology

Featured Article: Recombination landscape of the Nama population

Call for Papers: Interpretable Deep Learning Special Issue

Articles

BindVAE: Dirichlet variational autoencoders for de novo motif discovery from accessible chromatin

Single-cell diploid Hi-C reveals the role of spatial aggregations in complex rearrangements and KMT2A fusions in leukemia

The recombination landscape of the Khoe-San likely represents the upper limits of recombination divergence in humans

A benchmark study of deep learning-based multi-omics data fusion methods for cancer

Balanced mitochondrial and cytosolic translatomes underlie the biogenesis of human respiratory complexes

The Kardashian index: a measure of discrepant social media profile for scientists

A survey of best practices for RNA-seq data analysis

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Differential expression analysis for sequence count data

Latest articles from Genome Medicine

Molecular profiling of human non-small cell lung cancer by single-cell RNA-seq

Improved SARS-CoV-2 sequencing surveillance allows the identification of new variants and signatures in infected patients

Limited evidence for blood eQTLs in human sexual dimorphism

Focus: Fertility

Reviews, Research highlights and commentaries

Latest article collections

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From the blog

Exploring the history of smallpox vaccination with 19th Century American vaccination kits

Transposon Day Quiz 2020

DNA Day quiz 2020

Reviewer Acknowledgements 2020

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