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Featured article: Regulatory changes in cis and trans and evolution of gene expression in humans and chimpanzees

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Dosage compensation of Z sex chromosome genes in avian fibroblast cells

Authors: Ruslan Deviatiiarov, Hiroki Nagai, Galym Ismagulov, Anastasia Stupina, Kazuhiro Wada, Shinji Ide, Noriyuki Toji, Heng Zhang, Woranop Sukparangsi, Sittipon Intarapat, Oleg Gusev and Guojun Sheng

Content type: Short Report 20 September 2023
DISCERN: deep single-cell expression reconstruction for improved cell clustering and cell subtype and state detection

Authors: Fabian Hausmann, Can Ergen, Robin Khatri, Mohamed Marouf, Sonja Hänzelmann, Nicola Gagliani, Samuel Huber, Pierre Machart and Stefan Bonn

Content type: Research 20 September 2023
Structural variation and introgression from wild populations in East Asian cattle genomes confer adaptation to local environment

Authors: Xiaoting Xia, Fengwei Zhang, Shuang Li, Xiaoyu Luo, Lixin Peng, Zheng Dong, Hubert Pausch, Alexander S. Leonard, Danang Crysnanto, Shikang Wang, Bin Tong, Johannes A. Lenstra, Jianlin Han, Fuyong Li, Tieshan Xu, Lihong Gu…

Content type: Research 18 September 2023
Disparities in spatially variable gene calling highlight the need for benchmarking spatial transcriptomics methods

Authors: Natalie Charitakis, Agus Salim, Adam T. Piers, Kevin I. Watt, Enzo R. Porrello, David A. Elliott and Mirana Ramialison

Content type: Short Report 18 September 2023
Coupling of co-transcriptional splicing and 3’ end Pol II pausing during termination in Arabidopsis

Authors: Sixian Zhou, Fengli Zhao, Danling Zhu, Qiqi Zhang, Ziwei Dai and Zhe Wu

Content type: Research 11 September 2023

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A survey of best practices for RNA-seq data analysis

Authors: Ana Conesa, Pedro Madrigal, Sonia Tarazona, David Gomez-Cabrero, Alejandra Cervera, Andrew McPherson, Michał Wojciech Szcześniak, Daniel J. Gaffney, Laura L. Elo, Xuegong Zhang and Ali Mortazavi

Content type: Review 26 January 2016

The Erratum to this article has been published in Genome Biology 2016 17:181
The Kardashian index: a measure of discrepant social media profile for scientists

Authors: Neil Hall

Content type: Comment 30 July 2014
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Authors: Michael I Love, Wolfgang Huber and Simon Anders

Content type: METHOD 5 December 2014
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Authors: Jo Vandesompele, Katleen De Preter, Filip Pattyn, Bruce Poppe, Nadine Van Roy, Anne De Paepe and Frank Speleman

Content type: Research 18 June 2002
Differential expression analysis for sequence count data

Authors: Simon Anders and Wolfgang Huber

Content type: Method 27 October 2010

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Genome Biology

Featured article: Regulatory changes in cis and trans and evolution of gene expression in humans and chimpanzees

Featured article: Structural variation and introgression from wild populations in East Asian cattle genomes confer adaptation to local environment

Articles

Dosage compensation of Z sex chromosome genes in avian fibroblast cells

DISCERN: deep single-cell expression reconstruction for improved cell clustering and cell subtype and state detection

Structural variation and introgression from wild populations in East Asian cattle genomes confer adaptation to local environment

Disparities in spatially variable gene calling highlight the need for benchmarking spatial transcriptomics methods

Coupling of co-transcriptional splicing and 3’ end Pol II pausing during termination in Arabidopsis

A survey of best practices for RNA-seq data analysis

The Kardashian index: a measure of discrepant social media profile for scientists

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Differential expression analysis for sequence count data

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Long-read sequencing reveals the landscape of aberrant alternative splicing and novel therapeutic target in colorectal cancer

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Identification of novel protein biomarkers and drug targets for colorectal cancer by integrating human plasma proteome with genome

Focus: Fertility

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Exploring the history of smallpox vaccination with 19th Century American vaccination kits

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