Genome Biology

Featured article: Dengue and Zika RNA-RNA interactomes reveal pro- and anti-viral RNA in human cells

Featured article: Multi-omics analysis reveals the molecular response to heat stress in a “red tide” dinoflagellate

Call for papers: We are pleased to launch this new article collection which will welcome papers on all aspects of subcellular organization, mechanisms, and interactions.

Call for Papers: We are pleased to launch an article collection on insights from genomic and related research across diverse ancestries.

DNA methylation modulated genetic variant effect on gene transcriptional regulation

Authors: Yong Zeng, Rahi Jain, Magnus Lam, Musaddeque Ahmed, Haiyang Guo, Wenjie Xu, Yuan Zhong, Gong-Hong Wei, Wei Xu and Housheng Hansen He

Content type: Research 8 December 2023
Pediatric glioma histone H3.3 K27M/G34R mutations drive abnormalities in PML nuclear bodies

Authors: Hsiao P. J. Voon, Linda Hii, Andrew Garvie, Maheshi Udugama, Brian Krug, Caterina Russo, Anderly C. Chüeh, Roger J. Daly, Alison Morey, Toby D. M. Bell, Stephen J. Turner, Joseph Rosenbluh, Paul Daniel, Ron Firestein, Jeffrey R. Mann, Philippe Collas…

Content type: Research 8 December 2023
Turnover of strain-level diversity modulates functional traits in the honeybee gut microbiome between nurses and foragers

Authors: Gilles L. C. Baud, Aiswarya Prasad, Kirsten M. Ellegaard and Philipp Engel

Content type: Research 8 December 2023
Cotton pedigree genome reveals restriction of cultivar-driven strategy in cotton breeding

Authors: Shang Liu, Dongyun Zuo, Hailiang Cheng, Man He, Qiaolian Wang, Limin Lv, Youping Zhang, Javaria Ashraf, Ji Liu and Guoli Song

Content type: Research 8 December 2023
GCLiPP: global crosslinking and protein purification method for constructing high-resolution occupancy maps for RNA binding proteins

Authors: Wandi S. Zhu, Adam J. Litterman, Harshaan S. Sekhon, Robin Kageyama, Maya M. Arce, Kimberly E. Taylor, Wenxue Zhao, Lindsey A. Criswell, Noah Zaitlen, David J. Erle and K. Mark Ansel

Content type: Method 7 December 2023

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A survey of best practices for RNA-seq data analysis

Authors: Ana Conesa, Pedro Madrigal, Sonia Tarazona, David Gomez-Cabrero, Alejandra Cervera, Andrew McPherson, Michał Wojciech Szcześniak, Daniel J. Gaffney, Laura L. Elo, Xuegong Zhang and Ali Mortazavi

Content type: Review 26 January 2016

The Erratum to this article has been published in Genome Biology 2016 17:181
The Kardashian index: a measure of discrepant social media profile for scientists

Authors: Neil Hall

Content type: Comment 30 July 2014
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Authors: Michael I Love, Wolfgang Huber and Simon Anders

Content type: METHOD 5 December 2014
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Authors: Jo Vandesompele, Katleen De Preter, Filip Pattyn, Bruce Poppe, Nadine Van Roy, Anne De Paepe and Frank Speleman

Content type: Research 18 June 2002
Differential expression analysis for sequence count data

Authors: Simon Anders and Wolfgang Huber

Content type: Method 27 October 2010

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Latest articles from Genome Medicine

Focus: Fertility

Read the latest papers on fertility across BMC flagship journals.

Cisplatin and carboplatin result in similar gonadotoxicity in immature human testis with implications for fertility preservation in childhood cancer
Melissa D. Tharmalingam et al.

Published in BMC Medicine 04 December 2020

Large-scale discovery of male reproductive tract-specific genes through analysis of RNA-seq datasets
Matthew Robertson et al.

Published in BMC Biology 19 August 2020

DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies
Florianne Vehmeijer et al.

Published in Genome Medicine 25 November 2020

The Tug1 lncRNA locus is essential for male fertility
Jordan Lewandowski et al.

Published in Genome Biology 07 September 2020

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Exploring the history of smallpox vaccination with 19th Century American vaccination kits

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Genome Biology

Featured article: Dengue and Zika RNA-RNA interactomes reveal pro- and anti-viral RNA in human cells

Featured article: Multi-omics analysis reveals the molecular response to heat stress in a “red tide” dinoflagellate

Call for papers: We are pleased to launch this new article collection which will welcome papers on all aspects of subcellular organization, mechanisms, and interactions.

Call for Papers: We are pleased to launch an article collection on insights from genomic and related research across diverse ancestries.

Articles

DNA methylation modulated genetic variant effect on gene transcriptional regulation

Pediatric glioma histone H3.3 K27M/G34R mutations drive abnormalities in PML nuclear bodies

Turnover of strain-level diversity modulates functional traits in the honeybee gut microbiome between nurses and foragers

Cotton pedigree genome reveals restriction of cultivar-driven strategy in cotton breeding

GCLiPP: global crosslinking and protein purification method for constructing high-resolution occupancy maps for RNA binding proteins

A survey of best practices for RNA-seq data analysis

The Kardashian index: a measure of discrepant social media profile for scientists

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Differential expression analysis for sequence count data

Latest articles from Genome Medicine

Prenatal BRCA1 epimutations contribute significantly to triple-negative breast cancer development

Mendelian randomization analyses suggest a causal role for circulating GIP and IL-1RA levels in homeostatic model assessment-derived measures of β-cell function and insulin sensitivity in Africans without type 2 diabetes

Mobilizable plasmids drive the spread of antimicrobial resistance genes and virulence genes in Klebsiella pneumoniae

Focus: Fertility

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From the blog

Exploring the history of smallpox vaccination with 19th Century American vaccination kits

Transposon Day Quiz 2020

DNA Day quiz 2020

Reviewer Acknowledgements 2020

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