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Featured Article: The swan genome and transcriptome, it is not all black and white

Featured article: NetAct: a computational platform to construct core transcription factor regulatory networks using gene activity

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The collateral activity of RfxCas13d can induce lethality in a RfxCas13d knock-in mouse model

Authors: Yunfei Li, Junjie Xu, Xuefei Guo, Zhiwei Li, Lili Cao, Shengde Liu, Ying Guo, Guodong Wang, Yujie Luo, Zeming Zhang, Xuemei Wei, Yingchi Zhao, Tongtong Liu, Xiao Wang, Huawei Xia, Ming Kuang…

Content type: Research 1 February 2023
A pangenome analysis pipeline provides insights into functional gene identification in rice

Authors: Jian Wang, Wu Yang, Shaohong Zhang, Haifei Hu, Yuxuan Yuan, Jingfang Dong, Luo Chen, Yamei Ma, Tifeng Yang, Lian Zhou, Jiansong Chen, Bin Liu, Chengdao Li, David Edwards and Junliang Zhao

Content type: Research 26 January 2023
Auxin-inducible degron 2 system deciphers functions of CTCF domains in transcriptional regulation

Authors: Judith Hyle, Mohamed Nadhir Djekidel, Justin Williams, Shaela Wright, Ying Shao, Beisi Xu and Chunliang Li

Content type: Research 26 January 2023
β-actin mediated H3K27ac changes demonstrate the link between compartment switching and enhancer-dependent transcriptional regulation

Authors: Syed Raza Mahmood, Nadine Hosny El Said, Kristin C. Gunsalus and Piergiorgio Percipalle

Content type: Research 25 January 2023
The mechanism underlying redundant functions of the YTHDF proteins

Authors: Zhongyu Zou, Caraline Sepich-Poore, Xiaoming Zhou, Jiangbo Wei and Chuan He

Content type: Short Report 24 January 2023

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The Kardashian index: a measure of discrepant social media profile for scientists

Authors: Neil Hall

Content type: Comment 30 July 2014
A survey of best practices for RNA-seq data analysis

Authors: Ana Conesa, Pedro Madrigal, Sonia Tarazona, David Gomez-Cabrero, Alejandra Cervera, Andrew McPherson, Michał Wojciech Szcześniak, Daniel J. Gaffney, Laura L. Elo, Xuegong Zhang and Ali Mortazavi

Content type: Review 26 January 2016

The Erratum to this article has been published in Genome Biology 2016 17:181
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Authors: Michael I Love, Wolfgang Huber and Simon Anders

Content type: METHOD 5 December 2014
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Authors: Jo Vandesompele, Katleen De Preter, Filip Pattyn, Bruce Poppe, Nadine Van Roy, Anne De Paepe and Frank Speleman

Content type: Research 18 June 2002
Differential expression analysis for sequence count data

Authors: Simon Anders and Wolfgang Huber

Content type: Method 27 October 2010

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The genomic landscape of rare disorders in the Middle East

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Exploring the history of smallpox vaccination with 19th Century American vaccination kits

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Reviewer Acknowledgements 2020

The Editors and staff of Genome Biology would like to warmly thank the Reviewers whose comments helped to shape the journal, for their invaluable assistance with review of manuscripts in 2020.

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Genome Biology

Featured Article: The swan genome and transcriptome, it is not all black and white

Featured article: NetAct: a computational platform to construct core transcription factor regulatory networks using gene activity

Articles

The collateral activity of RfxCas13d can induce lethality in a RfxCas13d knock-in mouse model

A pangenome analysis pipeline provides insights into functional gene identification in rice

Auxin-inducible degron 2 system deciphers functions of CTCF domains in transcriptional regulation

β-actin mediated H3K27ac changes demonstrate the link between compartment switching and enhancer-dependent transcriptional regulation

The mechanism underlying redundant functions of the YTHDF proteins

The Kardashian index: a measure of discrepant social media profile for scientists

A survey of best practices for RNA-seq data analysis

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Differential expression analysis for sequence count data

Latest articles from Genome Medicine

The genomic landscape of rare disorders in the Middle East

Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry

The neuroimmune axis of Alzheimer’s disease

Focus: Fertility

Reviews, Research highlights and commentaries

Latest article collections

Latest Tweets

From the blog

Exploring the history of smallpox vaccination with 19th Century American vaccination kits

Transposon Day Quiz 2020

DNA Day quiz 2020

Reviewer Acknowledgements 2020

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