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Page 149 of 150

  1. The availability of complete genomic sequences of Saccharomyces cerevisiae has catalyzed a cultural change in the practice of yeast biology, providing opportunities to develop high throughput techniques to define...

    Authors: Charles Brenner
    Citation: Genome Biology 2000 1:reviews103.1
  2. The key molecules involved in regulating the assembly and function of the mitotic spindle are shared by evolutionarily divergent species. Studies in different model systems are leading to convergent conclusion...

    Authors: Claire E Walczak
    Citation: Genome Biology 2000 1:reviews101.1
  3. The use of cDNA microarrays for the study and mapping of gene amplifications and deletions on a whole-genome scale provides a comparison of DNA copy numbers in normal and tumor cells at unprecedented resolution.

    Authors: Aude Fahrer
    Citation: Genome Biology 2000 1:reports011
  4. This simple but incredibly useful tool for molecular biologists allows the user to select one or more restriction endonuclease enzymes and determine which of the enzyme buffers provided by New England Biolabs,...

    Authors: Todd Richmond
    Citation: Genome Biology 2000 1:reports232
  5. The particular interest of David Ussery and his group is in creating 'structural atlases' of genomes from a detailed analysis of variations in DNA structure.

    Authors: Shuba Gopal
    Citation: Genome Biology 2000 1:reports231
  6. UniGene, a gene indexing database, is at present the most substantial repository of transcript information from human, rat, mouse and zebrafish.

    Authors: Colin Semple
    Citation: Genome Biology 2000 1:reports230
  7. For those interested in DT40, a chick pre-B-cell line proving increasingly popular for use in gene targeting projects, this is a very useful site.

    Authors: Julie Curran
    Citation: Genome Biology 2000 1:reports227
  8. Detailed descriptions of the design and information content of EBI's database ArrayExpress, which is currently under development but aims to be a public repository of gene expression data, are the main feature...

    Authors: Paul Kellam
    Citation: Genome Biology 2000 1:reports226
  9. Several programs to predict sequence and structural features of a protein can be run simultaneously on the PredictProtein server.

    Authors: Mar Albà
    Citation: Genome Biology 2000 1:reports225
  10. The NetGene2 server uses a neural network combined with a rule-based system to predict intron splice sites in Arabidopsis thaliana, Caenorhabditis elegansand humans.

    Authors: Todd Richmond
    Citation: Genome Biology 2000 1:reports223
  11. Data are collected from Nature, Science, Cell, and Nature Cell Biologyto form a database and resource for the signaling pathways of human cells.

    Authors: Iain Gilfillan
    Citation: Genome Biology 2000 1:reports221
  12. This online version of a US Department of Energy publication provides detailed background information about the human genome project.

    Authors: Basil Safwat
    Citation: Genome Biology 2000 1:reports215
  13. This site has a collection of features dealing with different areas of genetic research, and is an interesting and useful piece of 'popular science'.

    Authors: Basil Safwat
    Citation: Genome Biology 2000 1:reports213
  14. The puffer fish Fugu rubripes is perhaps better known as a Japanese delicacy, but its gene-rich, relatively small genome makes the puffer fish a suitable vertebrate for comparative mapping.

    Authors: Aengus Stewart
    Citation: Genome Biology 2000 1:reports210
  15. This comprehensive online biology reference book consists of lists of terms covering an extensive range of biological topics, and is aimed primarily at graduate students.

    Authors: Ines Chyla
    Citation: Genome Biology 2000 1:reports207
  16. A great site for anyone interested in breast cancer or mammary gland development - beginners and experienced researchers alike.

    Authors: Bryony Wiseman
    Citation: Genome Biology 2000 1:reports206
  17. SYFPEITHI, a database of interactions between proteins of the major histocompatibility complex (MHC) and antigenic peptides, contains information on MHC-associated peptide sequences, anchor positions, MHC mole...

    Authors: Christopher J Thorpe
    Citation: Genome Biology 2000 1:reports203
  18. The first publication of the genomic sequence of an entire human chromosome.

    Authors: Jonathan B Weitzman
    Citation: Genome Biology 2000 1:reports019
  19. Plant defense responses are induced by recognition of a conserved epitope of the major protein of the bacterial flagellum. This could represent a general perception mechanism for plants to detect infection by ...

    Authors: William Deakin
    Citation: Genome Biology 2000 1:reports013
  20. Bioinformatic analysis has been used to identify gene-fusion events in complete genomes and thus infer protein interactions on the basis of sequence analysis alone.

    Authors: Paul Kellam
    Citation: Genome Biology 2000 1:reports009
  21. The isolation of a putative receptor protein for rhizobial nod factors that is located on the surface of legume roots and also has nucleotide hydrolytic properties is described.

    Authors: William Deakin
    Citation: Genome Biology 2000 1:reports007
  22. Protein virulence factors can be secreted from bacterial cells using the machinery used to assemble the flagellum.

    Authors: William Deakin
    Citation: Genome Biology 2000 1:reports003
  23. Mice with a disrupted Gadd45a gene share several phenotypic characteristics with p53 knockout mice, including genomic instability, increased carcinogenesis and exencephaly.

    Authors: Jonathan B Weitzman
    Citation: Genome Biology 2000 1:reports002
  24. YopJ, a virulence factor of Yersinia pseudotuberculosis, can bind to several key intracellular signaling proteins, members of the MAPKK family, preventing their activation and protecting the pathogen from host de...

    Authors: Jonathan B Weitzman
    Citation: Genome Biology 2000 1:reports001

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