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A report on the Royal Society Discussion Meeting "The plant cell: between genome and plant", London, 13-14 June 2001.
A report on the Cold Spring Harbor meeting on Genome Sequencing and Biology, Cold Spring Harbor, NY, USA, 9-13 May 2001.
A response to The complete genome sequence of Vibrio cholerae : a tale of two chromosomes and of two lifestyles, by Gary K Schoolnik and Fitnat H Yildiz, Genome Biology 2000 1:reviews1016.1-1016.3.
We propose two different formulations of the Rasch statistical models to the problem of relating gene expression profiles to the phenotypes. One formulation allows us to investigate whether a cluster of genes ...
The DNA sequence of one of the smallest eukaryotic genomes has recently been finished - that of the reduced nucleus, or nucleomorph, of an algal endosymbiont that resides within a cryptomonad host cell. Its se...
Chlorophyll precursors, photosynthetic electron transport, and sugars have all been shown to be involved in signaling from the chloroplast to the nucleus, suggesting the presence of multiple signaling pathways...
Geneimprint.com is dedicated to providing information about imprinted genes for researchers, students and others interested in the subject.
BodyMap is a database of human and mouse gene expression organized according to the anatomical origin of the tissue.
The mfold server has a simple interface that allows any researcher to analyze a submitted RNA sequence for various secondary structures using up-to-date algorithms and free-energy rules.
COPE is the electronic updated version of the Dictionary of Cytokines (Wiley; New York:1994) and represents a comprehensive online reference guide to the field of cytokine research.
Chorismate mutases of the AroQ homology class are widespread in the Bacteria and the Archaea. Many of these exist as domains that are fused with other aromatic-pathway catalytic domains. Among the monofunction...
The availability of complete genome sequences enables all the members of a gene family to be identified without limitations imposed by temporal, spatial or quantitative aspects of mRNA expression. Using the ne...
The Master Catalog is a collection of evolutionary families, including multiple sequence alignments, phylogenetic trees and reconstructed ancestral sequences, for all protein-sequence modules encoded by genes ...
TBASE is a database of information on all transgenic mice and targeted mutations, with particular emphasis on knockouts.
A multiple copy gene family on the human Y chromosome has been shown to be transcribed but not translated.
A novel protein upregulated in certain cancers has been identified and characterized using an integrated proteomics, genomics, bioinformatics and standard molecular biology approach.
Recombinant inbred (RI) strains of mice are an important resource used to map and analyze complex traits. They have proved particularly effective in multidisciplinary genetic studies. Widespread use of RI stra...
The primary sequence of Xist seems not to be important for Xist to function in X-chromosome inactivation.
Apoptosis is a physiological cell death process important for development, homeostasis and the immune defence of multicellular animals. The key effectors of apoptosis are caspases, cysteine proteases that clea...
In most eukaryotes, histones, which are the major structural components of chromatin, are expressed as a family of sequence variants encoded by multiple genes. Because different histone variants can contribute...
The recent draft assembly of the human genome provides a unified basis for describing genomic structure and function. The draft is sufficiently accurate to provide useful annotation, enabling direct observatio...
A report on Novartis Foundation Symposium 244 "The Genetics and Biology of Sex Determination", London, UK, 1-3 May 2001.
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