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The tumor gene database is a searchable database of information on over 300 known tumor genes. The information is broken down into 'fact' headings for each gene.
Motor neuron identity and target selection are primarily genetically controlled.
Analysis of families suffering from total color blindness has revealed one potential cause of the condition - mutations in a gene encoding a α subunit of the retinal cone cGMP-gated ion channel.
Genes expressed during C. elegans germline development have been identified using DNA microarrays.
Nanodroplets of active, solvated protein can be printed onto treated glass slides for protein microarray experiments.
Isolated SNARE proteins have been shown to confer only partial specificity on the fusion of artificial liposomes that mimic cellular membranes, modifying the SNARE hypothesis of membrane fusion.
The importance of the lens in eye development has been demonstrated using reciprocal transplantations between an eyed surface-dwelling fish and an eyeless cave fish of the same species.
A report on the Third Genetic Effects on Aging Meeting, The Jackson Laboratory, Bar Harbor, Maine, August 4-8, 2000.
Much is expected of the draft human genome sequence, and yet there is no central resource to host the plethora of sequence and mapping information available. Consequently, finding the most useful and reliable ...
Rat Nb2-11C lymphoma cells are dependent on prolactin for proliferation and are widely used to study prolactin signaling pathways. To investigate the role of this hormone in the transcriptional mechanisms that...
Cellulose, an aggregate of unbranched polymers of β-1,4-linked glucose residues, is the major component of wood and thus paper, and is synthesized by plants, most algae, some bacteria and fungi, and even some ...
The origin of the relict chloroplast recently identified in malarial parasites has been mysterious. Several new papers suggest that the parasites obtained their chloroplasts in an ancient endosymbiotic event t...
A new mechanism for regulation in the immune system has been identified: a cytidine deaminase is critical for both class switch recombination and somatic hypermutation, revealing an unanticipated link between ...
Uracil DNA glycosylases (UDGs) are major repair enzymes that protect DNA from mutational damage caused by uracil incorporated as a result of a polymerase error or deamination of cytosine. Four distinct familie...
Potassium channels, tetrameric integral membrane proteins that form aqueous pores through which K+ can flow, are found in virtually all organisms; the genomes of humans, Drosophila, and Caenorhabditis elegans con...
A report on the 'Nuclear architecture and control of gene expression' minisymposium at the first meeting of the European Life Scientists Organisation (ELSO), Geneva, Switzerland, September 2-6, 2000.
A report of the Molecular Genetics of Model Legumes meeting, John Innes Centre, Norwich, 24-28 June, 2000.
Profiling of gene expression in bacteria is now being used to uncover unknown genes expressed in particular genetic backgrounds or environmental conditions. Obtaining the best possible information from the exp...
The genetic and molecular analysis of circadian timekeeping mechanisms has accelerated as a result of the increasing volume of genomic markers and nucleotide sequence information. Completion of whole genome se...
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