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  1. Sophisticated molecular biological research has revealed many virulence attributes in at least four pathogenic fungi, but the future study of fungal virulence requires investigators to distinguish between mole...

    Authors: Frank C Odds, Neil AR Gow and Alistair JP Brown
    Citation: Genome Biology 2001 2:reviews1009.1
  2. Oligonucleotide and cDNA microarrays have been used to analyse the mRNA levels of 8,000 genes in Arabidopsis thaliana throughout the day/night cycle. Genes involved in signal transduction and in various metabolic...

    Authors: Seth J Davis and Andrew J Millar
    Citation: Genome Biology 2001 2:reviews1008.1
  3. Once thought to be impossible or a waste of resources, the initial high-volume stages of sequencing the human genome have been completed.

    Authors: Colin AM Semple, Kathryn L Evans and David J Porteous
    Citation: Genome Biology 2001 2:comment2003.1
  4. A large-scale RNA interference screen has proved an efficient and powerful reverse genetic approach for identifying genes involved in cell division in Caenorhabditis elegans.

    Authors: Joe Hao
    Citation: Genome Biology 2001 2:reports0008
  5. A method for double-stranded RNA interference of gene expression in mammalian cells.

    Authors: Edupalli Subbaiah Venkata
    Citation: Genome Biology 2001 2:reports0007
  6. SAGE is a genome-wide method for obtaining gene expression profiles. It generates tags of 10 nucleotides in length, which are assumed to determine the corresponding gene transcript. In practice however, this i...

    Authors: Jacques Colinge and Georg Feger
    Citation: Genome Biology 2001 2:preprint0002.1
  7. Classic methods of identifying genes involved in neural function include the laborious process of behavioral screening of mutagenized flies and then rescreening candidate lines for pleiotropic effects due to d...

    Authors: Karen L Posey, Leslie B Jones, Rosalinda Cerda, Monica Bajaj, Thao Huynh, Paul E Hardin and Susan H Hardin
    Citation: Genome Biology 2001 2:research0008.1
  8. The recent draft assembly of the human genome provides a unified basis for describing genomic structure and function. The draft is sufficiently accurate to provide useful annotation, enabling direct observatio...

    Authors: Fred A Wright, William J Lemon, Wei D Zhao, Russell Sears, Degen Zhuo, Jian-Ping Wang, Hee-Yung Yang, Troy Baer, Don Stredney, Joe Spitzner, Al Stutz, Ralf Krahe and Bo Yuan
    Citation: Genome Biology 2001 2:preprint0001.1
  9. What is the minimum number of genes or functions necessary to support cellular life? The concept of a 'minimal genome' has become popular, but is it a useful concept, and if so, what might a minimal genome enc...

    Authors: Scott N Peterson and Claire M Fraser
    Citation: Genome Biology 2001 2:comment2002.1
  10. Large-scale expression profiling has revealed distinct clusters of circadian clock-regulated genes and identified a phase-specific cis-regulatory element.

    Authors: Thomas Eulgem
    Citation: Genome Biology 2001 2:reports0005
  11. A comparative study based on four fully sequenced eukaryotic genomes has revealed profound differences in the sets of transcription factors used by plants, fungi and animals.

    Authors: Thomas Eulgem
    Citation: Genome Biology 2001 2:reports0004
  12. A report on the British Society for Immunology Annual Congress, Harrogate, UK, 5-8 December 2000.

    Authors: Rachel L Allen
    Citation: Genome Biology 2001 2:reports4004.1
  13. A report on the 'Critical Assessment of Microarray Data Analysis' (CAMDA 2000) meeting, Durham, North Carolina, USA, December 18-19,2000.

    Authors: James N Siedow
    Citation: Genome Biology 2001 2:reports4003.1
  14. A report on the talks presented at the Cold Spring Harbor 2000 Meeting on Arabidopsis Genomics, New York, 7-10 December, 2000.

    Authors: Pablo D Rabinowicz and Mary E Byrne
    Citation: Genome Biology 2001 2:reports4002.1
  15. Uridine diphosphate (UDP) glycosyltransferases (UGTs) mediate the transfer of glycosyl residues from activated nucleotide sugars to acceptor molecules (aglycones), thus regulating properties of the acceptors s...

    Authors: Joe Ross, Yi Li, Eng-Kiat Lim and Dianna J Bowles
    Citation: Genome Biology 2001 2:reviews3004.1
  16. Chloride-conducting ion channels of the ClC family are emerging as critical contributors to a host of biological processes. These polytopic membrane proteins form aqueous pathways through which anions are sele...

    Authors: Joe Mindell and Merritt Maduke
    Citation: Genome Biology 2001 2:reviews3003.1

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