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  1. Microarray analysis has confirmed that many of the modifications of gene expression that occur in plants following attack by herbivorous insects can be accounted for by the effects of compounds (elicitors) rel...

    Authors: Kenneth L Korth
    Citation: Genome Biology 2003 4:221
  2. The olfactory systems of insects and mammals have analogous anatomical features and use similar molecular logic for olfactory coding. The molecular underpinnings of the chemosensory systems that detect taste a...

    Authors: Hiroaki Matsunami and Hubert Amrein
    Citation: Genome Biology 2003 4:220
  3. MicroRNAs (miRNAs) are a large family of 21-22 nucleotide non-coding RNAs with presumed post-transcriptional regulatory activity. Most miRNAs were identified by direct cloning of small RNAs, an approach that f...

    Authors: Eric C Lai, Pavel Tomancak, Robert W Williams and Gerald M Rubin
    Citation: Genome Biology 2003 4:R42
  4. Transcriptional regulation in eukaryotes often involves multiple transcription factors binding to the same transcription control region, and to understand the regulatory content of eukaryotic genomes it is nec...

    Authors: Derek Y Chiang, Alan M Moses, Manolis Kellis, Eric S Lander and Michael B Eisen
    Citation: Genome Biology 2003 4:R43
  5. The recently sequenced genome of the filamentous fungus Ashbya gossypii revealed remarkable similarities to that of the budding yeast Saccharomyces cerevisiae both at the level of homology and synteny (conservati...

    Authors: Sophie Brachat, Fred S Dietrich, Sylvia Voegeli, Zhihong Zhang, Larissa Stuart, Anita Lerch, Krista Gates, Tom Gaffney and Peter Philippsen
    Citation: Genome Biology 2003 4:R45
  6. Tumor cells cultured in vitro are widely used to investigate the molecular biology of cancers and to evaluate responses to drugs and other agents. The full extent to which gene expression in cancer cells is modul...

    Authors: Chad Creighton, Rork Kuick, David E Misek, David S Rickman, Franck M Brichory, Jean-Marie Rouillard, Gilbert S Omenn and Samir Hanash
    Citation: Genome Biology 2003 4:R46
  7. A selection of evaluations from Faculty of 1000 covering the quantification of proteins and phosphoproteins, haplotype structure in Arabidopsis, genomewide analysis of small interfering RNAs, screening newborns f...

    Authors:
    Citation: Genome Biology 2003 4:330
  8. Subcellular messenger RNA localization is important in most eukaryotic cells, even in unicellular organisms like yeast for which this process has been underestimated. Microarrays are rarely used to study subce...

    Authors: Julien Sylvestre, Stéphane Vialette, Marisol Corral Debrinski and Claude Jacq
    Citation: Genome Biology 2003 4:R44
  9. A selection of evaluations from Faculty of 1000 covering the identification of cereal cell wall biosynthetic genes, off-target gene regulation by RNAi, protoemics of lipid rafts, a mating-type gene in Aspergillus...

    Authors:
    Citation: Genome Biology 2003 4:329
  10. We have derived a novel method to assess compositional biases in biological sequences, which is based on finding the lowest-probability subsequences for a given residue-type set. As a case study, the distribut...

    Authors: Paul M Harrison and Mark Gerstein
    Citation: Genome Biology 2003 4:R40
  11. The matrix metalloproteinase family in humans comprises 23 enzymes, which are involved in many biological processes and diseases. It was previously thought that these enzymes acted only to degrade components o...

    Authors: Robert PT Somerville, Samantha A Oblander and Suneel S Apte
    Citation: Genome Biology 2003 4:216
  12. Experimental analyses of the proteins found in the mitochondria of yeast, humans and Arabidopsis have confirmed some expectations but given some surprises and some insights into the evolutionary origins of mitoch...

    Authors: Joshua L Heazlewood, A Harvey Millar, David A Day and James Whelan
    Citation: Genome Biology 2003 4:218
  13. As an antioxidant and cofactor to numerous metabolic enzymes, ascorbate has an essential role in plants and animals. Cytochromes b561 constitute a class of intrinsic membrane proteins involved in ascorbate regene...

    Authors: Wim Verelst and Han Asard
    Citation: Genome Biology 2003 4:R38
  14. Bacterial communities that are attached to a surface, so-called biofilms, and their inherent resistance to antimicrobial agents are a cause of many persistent and chronic bacterial infections. Recent genomic a...

    Authors: Karin Sauer
    Citation: Genome Biology 2003 4:219

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