Genome Biology operates a single-blind peer-review system, where the reviewers are aware of the names and affiliations of the authors, but the reviewer reports provided to authors are anonymous. The benefit of single-blind peer-review is that it is the traditional model of peer review that many reviewers are comfortable with, and it facilitates a dispassionate critique of a manuscript.
Genome Biology considers articles that are scientifically valid and a useful contribution to the field. Articles must also be of interest to a broad readership of biologists and/or represent an exceptional advance within a specific field. Manuscripts are initially assessed by our experienced team of in-house editors, and those that are deemed of interest are sent for peer review. Peer reviewers primarily assess the scientific content and coherence of articles, but are also asked to comment on interest levels and advance.