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  1. A report from the Cold Spring Harbor Laboratory 2000 conference on Retroviruses, Cold Spring Harbor, May 23-28, 2000.

    Authors: Cecile Voisset and Mariam Andrawiss
    Citation: Genome Biology 2000 1:reports4015.1
  2. A series of reports - and extracts of reports - from the Freedom of Information Conference, 6-7 July, 2000, New York Academy of Medicine. The conference was sponsored by BioMed Central, to promote debate about...

    Authors: Harold Varmus, David Lipman, Paul Ginsparg and Barry P Markovitz
    Citation: Genome Biology 2000 1:comment2003.1
  3. A concurrence of genomic, reverse genetic and biochemical approaches has cracked the decade-long enigma concerning the identity of the transcription factors that control gene expression at the G2/M transition ...

    Authors: Paul Jorgensen and Mike Tyers
    Citation: Genome Biology 2000 1:reviews1022.1
  4. Transcriptional analysis of all the genes expressed by breast tumors has provided the first steps towards defining a molecular signature for the disease, and might ultimately make conventional diagnostic techn...

    Authors: Samuel AJR Aparicio, Carlos Caldas and Bruce Ponder
    Citation: Genome Biology 2000 1:reviews1021.1
  5. Genome-wide measures of DNA strand composition have been used to find archaeal DNA replication origins. Archaea seem to replicate using a single origin (as do eubacteria) even though archaeal replication facto...

    Authors: Amit Vas and Janet Leatherwood
    Citation: Genome Biology 2000 1:reviews1020.1
  6. The recently published genomic sequence of Xylella fastidiosa is the first for a free-living plant pathogen and provides clues to mechanisms of pathogenesis and survival in insect vectors. The sequence data shoul...

    Authors: Noel T Keen, C Korsi Dumenyo, Ching-Hong Yang and Donald A Cooksey
    Citation: Genome Biology 2000 1:reviews1019.1
  7. Key components of the programmed cell death pathway are conserved between Caenorhabditis elegans, Drosophila melanogaster and humans. The search for additional homologs has been facilitated by the availability of...

    Authors: Jan N Tittel and Hermann Steller
    Citation: Genome Biology 2000 1:reviews0003.1
  8. For most vertebrate organs and tissues, the majority of development occurs during embryogenesis, and postnatal changes are primarily concerned with growth. The central nervous system is unusual in that a consi...

    Authors: M Clinton, J Manson, D McBride and G Miele
    Citation: Genome Biology 2000 1:research0005.1
  9. A recent study, comparing the maize SILKY1 gene to its well-characterized homolog APETALA3 from Arabidopsis, has provided some of the first evidence pointing to conservation of homeotic gene function between mono...

    Authors: Vivian F Irish
    Citation: Genome Biology 2000 1:reviews1015.1
  10. Using DNA microarrays, 381 genes have been found to be induced in response to unfolded proteins. The identity of the previously characterized 208 of these, and further experiments, have revealed new details on...

    Authors: Ardythe A McCracken and Jeffrey L Brodsky
    Citation: Genome Biology 2000 1:reviews1013.1
  11. The budding yeast Saccharomyces cerevisiae and the fission yeast Schizosaccharomyces pombe are as different from each other as either is from animals: their ancestors separated about 420 to 330 million years ago....

    Authors: Matthias Sipiczki
    Citation: Genome Biology 2000 1:reviews1011.1
  12. Several studies are starting to show the power of DNA microarrays to identify interactions between animal hosts and their pathogens, and have revealed interesting correlations between host responses to differe...

    Authors: Paul Kellam
    Citation: Genome Biology 2000 1:reviews1009.1
  13. Large gene expression studies, such as those conducted using DNA arrays, often provide millions of different pieces of data. To address the problem of analyzing such data, we describe a statistical method, whi...

    Authors: Trevor Hastie, Robert Tibshirani, Michael B Eisen, Ash Alizadeh, Ronald Levy, Louis Staudt, Wing C Chan, David Botstein and Patrick Brown
    Citation: Genome Biology 2000 1:research0003.1

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