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Fig. 2 | Genome Biology

Fig. 2

From: Super-resolution visualization and modeling of human chromosomal regions reveals cohesin-dependent loop structures

Fig. 2

Super-resolution 3D imaging of chromosome regions. a Widefield 3D image of a single fluorescently labeled chromatin region (maximum intensity projection of a z-stack). b,c Super-resolution 3D images of the same structure obtained with ZOLA-3D [35]. b A color-coded view, where color indicates axial coordinate. c Two 500-nm-thick slices through the 3D super-resolution image are shown, with two 1ā€‰Ī¼mā€‰Ć—ā€‰1ā€‰Ī¼m regions (yellow boxes) shown magnified to the right. The white arrow points to an isolated piece of chromatin fiber. For an animated 3D view, see Additional fileĀ 2: Video S1

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