Fig. 4
![Fig. 4](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13059-016-1134-6/MediaObjects/13059_2016_1134_Fig4_HTML.gif)
Chronic OP exposure activates the gut microbiome xenobiotic metabolism genes. a Percentage of normalized counts assigned to each KEGG category module. b Expression profile of OP degrading genes expressed as reads per kilomillion counts (RPKM) (n = 3). c OGTT of animals fed with fecal culture/suspended cells/supernatant grown in the presence or absence of MCP (n = 10). d Fecal esterase activity of the animals fed with fecal culture/suspended cells/supernatant grown in the presence or absence of MCP (n = 6). Horizontal lines, bars, or symbols represent mean; error bars represent s.e.m; ***P < 0.001, *P < 0.05. Unpaired two-sided student-t test (b, d) or two-way ANOVA with Bonferroni correction (c). Experiments were repeated twice