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Erratum to: Dynamics of gene silencing during X inactivation using allele-specific RNA-seq

After the publication of this work [1], we noticed there was an error in Fig. 5 where −1,0 and 1 are incorrectly displayed in the y-axis in panel b. Please see the corrected Fig. 5 below. We apologize for this error.

Fig. 5
figure1

llele-specific RNA-seq on three NPC lines identifies three distal regions of genes that escape XCI. a Ratio of Xi/Xa (y-axis; for each of the three NPC lines sorted from highest to lowest) for genes showing a log2 ratio of at least −5. We set the cutoff for escape on 10 % relative expression from the Xi versus the Xa (log 2 ratio of > −3.32; similar to Yang et al. [37]). b Xi/Xa ratio of genes that escape XCI in all three NPC lines. c Distribution of the escape genes identified in *NPC_129-Xi over the four clusters as characterized in Fig. 4a. d Localization of the escape genes within each NPC line over the linear X chromosome (see also Table 1). The black dots on the fourth row represent all X-linked genes for which high-confidence allele-specific ratios were obtained in NPCs. e Validation of the escape genes within the three escape regions by Sanger sequencing of cDNA. See Additional file 1: Figure S13 for the full panel of 13 genes that we validated, and for further details

References

  1. 1.

    Marks H, Kerstens HH, Barakat TS, Splinter E, Dirks RAM, van Mierlo G, et al. Dynamics of gene silencing during X inactivation using allele-specific RNA-seq. Genome Biol. 2015;16:149.

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Correspondence to Hendrik Marks or Hendrik G. Stunnenberg.

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The online version of the original article can be found under doi:10.1186/s13059-015-0698-x.

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Marks, H., Kerstens, H.H.D., Barakat, T.S. et al. Erratum to: Dynamics of gene silencing during X inactivation using allele-specific RNA-seq. Genome Biol 17, 22 (2016). https://doi.org/10.1186/s13059-016-0885-4

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