Figure 6
From: Conserved syntenic clusters of protein coding genes are missing in birds
Bioinformatics analysis of avian missing genes. Breakdown of avian missing genes according to their association with: (A) The Ingenuity Pathway Functional enrichment categories related to Diseases and Disorders, Molecular and Cellular Functions, and Physiological System Development and Function (P <0.05; ranked according to number of genes), (B) organ and/or systems phenotypes associated with mouse knockout studies, and/or (C) genetic diseases and syndromes in humans that are also lethal when knocked out in mice. Further details are presented in Additional file 1: Tables S9-S13. * - includes both apoptotic and non-apoptotic; ** - includes clathrin related and receptor clustering; *** - includes kinases, phosphatases, and calmodulins, **** - includes glycosylation, methylation, and acetylation; † − [21].