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Table 1 Schizophrenia-associated differentially methylated positions in the prefrontal cortex

From: Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia

Probe ID Genomic position (hg19) Gene Gene region P -value FDR Mean SZ Mean control Beta difference
cg26173173 chr8:144642813 GSDMD Body 1.16E-07 0.03 0.83 0.79 0.04
cg24803255 chr13:114807060 RASA3 Body 1.25E-07 0.03 0.56 0.65 −0.09
cg00903099 chr7:154862441 HTR5A TSS200 2.40E-07 0.03 0.09 0.12 −0.02
cg08171022 chr11:70185278 PPFIA1 Body 2.85E-07 0.03 0.48 0.53 −0.05
cg02857643 chr17:48696108 CACNA1G Body 1.63E-06 0.1 0.87 0.92 −0.05
cg00236305 chr2:1796076 MYT1L Body 1.75E-06 0.1 0.67 0.73 −0.06
cg14966346 chr14:104152124 KLC1 Body 2.51E-06 0.1 0.72 0.77 −0.05
cg13079528 chr7:4027346 SDK1 Body 2.75E-06 0.1 0.71 0.79 −0.08
cg14429765 chr8:6492531 MCPH1 Body 2.79E-06 0.1 0.79 0.76 0.03
cg08602214 chr8:22864392 RHOBTB2 Body 2.87E-06 0.1 0.69 0.75 −0.07
cg19735533 chr2:241196887 - - 2.94E-06 0.1 0.76 0.81 −0.06
cg09507608 chr22:29873338 - - 2.95E-06 0.1 0.56 0.62 −0.06
cg23844013 chr1:57383752 C8A 3' UTR 3.20E-06 0.1 0.82 0.79 0.03
cg26578910 chr19:47204096 PRKD2 Body 3.47E-06 0.1 0.67 0.71 −0.04
cg21847368 chr13:113744010 MCF2L Body 3.70E-06 0.1 0.80 0.84 −0.03
cg03607729 chr16:25138698 LCMT1 Body 4.19E-06 0.1 0.70 0.75 −0.04
cg10248981 chr10:126157948 LHPP Body 4.32E-06 0.1 0.55 0.63 −0.07
cg03445663 chr2:242170236 HDLBP Body 4.59E-06 0.1 0.51 0.59 −0.08
cg15079231 chr3:42572745 VIPR1 Body 4.93E-06 0.1 0.76 0.80 −0.04
cg21341878 chr4:2278462 ZFYVE28 Body 5.14E-06 0.1 0.75 0.81 −0.05
cg04922803 chr12:104444418 GLT8D2 TSS1500 5.19E-06 0.1 0.68 0.62 0.06
cg18857062 chr6:43276478 CRIP3 Body 5.29E-06 0.1 0.21 0.26 −0.04
  1. Listed are all probes associated with schizophrenia (SZ) with FDR ≤0.1. The 100 top-ranked DMPs are listed in Table S4 in Additional file 1.