- Research news
- Published:
Replicating both ways
Genome Biology volume 1, Article number: spotlight-20000629-02 (2000)
Archeal DNA replication proteins are closely related to eukaryotic counterparts, but in the June 23 Science Myllykallio et al. report that the archeon Pyrococcus abyssi has a bacterial mode of replication (Science 2000, 288:2212-2215). Myllykallio et al. use the excess of G over C in the leading replication strand to identify a single origin of bi-directional replication in Pyrococcus. A comparison with a related archeon reveals that, as in bacteria, the replication terminus is a hotspot of genome shuffling. These two similarities with bacteria may be evidence for either convergent evolution or conservation of replication characteristics from the time of a common ancestor.
References
Archaea and the origin(s) of DNA replication proteins.
Science, [http://www.sciencemag.org/]
Rights and permissions
About this article
Cite this article
Wells, W. Replicating both ways. Genome Biol 1, spotlight-20000629-02 (2000). https://doi.org/10.1186/gb-spotlight-20000629-02
Published:
DOI: https://doi.org/10.1186/gb-spotlight-20000629-02
Keywords
- Common Ancestor
- Convergent Evolution
- Replication Protein
- Genome Shuffling
- Single Origin