Skip to main content

Advertisement

Stem cells branch out

Article metrics

  • 471 Accesses

Differentiation of embryonic stem (ES) cells, which are originally totipotent, puts increasing restrictions on the final fates that a cell can achieve. This simple idea was upset last year when neural stem cells were shown to produce blood cells in irradiated adult mice. In the 2 June issue of Science, Clarke et al. show that neural stem cells injected into embryos can generate a wide variety of tissues including cells in the central nervous system, heart, liver, and intestine (Science 2000, 288:1660-1663). This raises the possibility of using similar stem cells for human therapy, in place of the ethically questionable use of human ES cells.

References

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Wells, W. Stem cells branch out. Genome Biol 1, spotlight-20000607-02 (2000) doi:10.1186/gb-spotlight-20000607-02

Download citation

Keywords

  • Stem Cell
  • Nervous System
  • Central Nervous System
  • Blood Cell
  • Embryonic Stem