Volume 11 Supplement 1
MamPhEA: a web tool for mammalian phenotype enrichment analysis
© Weng and Liao; licensee BioMed Central Ltd. 2010
Published: 11 October 2010
Most mouse (Mus musculus) mutants generated in laboratories have been designed to aid the study of human genetics, physiology or diseases progression. To date, nearly 9000 genes in the mouse genome have been mutated; these have been phenotyped in such a way that resembles human clinical examinations. The mutant phenotypes characterize the consequence of disturbing or disrupting the information output of a gene and thus are ideal to aid understanding of how genes function at the systems level. Therefore, enrichment analyses incorporating mouse mutant phenotypes are particularly useful in studying mammalian functional genomics in the post-genome era.
- Weng Meng-Pin, Liao Ben-Yang: MamPhEA: a Web tool for Mammalian Phenotype Enrichment Analysis. Bioinformatics. 2010.Google Scholar
This article is published under license to BioMed Central Ltd.