Reproducibility of target enrichment. (a) The normalized mean coverage of each capture probe is plotted for the technical replicates of NA15510 and HE00069 (Capture 1 versus Capture 2). Capture probes that lie outside the dashed lines on the plot have normalized coverage that differs by more than twofold in the technical replicates. (b) The normalized mean coverage of each capture probe is plotted for NA15510 (Capture 1) versus HE00069 (Capture 1). The values of coefficient of determination (r2) are shown.