Figure 5
From: Systematic quantification of gene interactions by phenotypic array analysis
An enlarged view of clusters 2 and 3 from Figure 4. (a) Cluster 2 identifies a group of strains indicating strong and selective synergism between gene deletion and DNA-damaging perturbations. The set is highly enriched for DNA repair genes, and, in particular, homologous recombination genes. (b) Cluster 3 identifies genes required for growth under all perturbations tested, and is enriched for genes involved in vesicular trafficking, most notably vacuolar protein sorting. Gene names are from SGD and descriptions can be found in Additional data file 10 [47]. Abbreviations as in Figure 4.