Table 4 The location of the regions improved by 25% reference bias when using LevioSAM 2 compared to the direct-to-GRC method. A biased region was “Near Centromere” if it locates within 500 kbp of a region annotated as centromeric by the UCSC genome browser
From: Measuring, visualizing, and diagnosing reference bias with biastools
bases improved | Total | Near centromere | Away from centromere |
|---|---|---|---|
All regions | 6,132,182 | 2,304,633 (38%) | 3,827,549 (62%) |
Regions > 1000 bp | 5,631,958 | 2,242,093 (40%) | 3,389,865 (60%) |