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Fig. 3 | Genome Biology

Fig. 3

From: Seven-chain adaptive immune receptor repertoire analysis in rheumatoid arthritis reveals novel features associated with disease and clinically relevant phenotypes

Fig. 3

Chain and gene segment usage profiles of rheumatoid arthritis patients. a Differences in the whole blood usage of each immune receptor chain between rheumatoid arthritis and healthy individuals. Differences in the percentage of IGK reads from the total pool of IGK and IGL reads are also shown. b Differences in the usage of each immune receptor chain between whole blood and synovium samples from patients with rheumatoid arthritis. c First two principal components of the V gene segment usage (N = 298 variables from the seven immune receptor chains) in rheumatoid arthritis and controls. d First two principal components of the J gene segment usage (N = 100 variables from the seven immune receptor chains) in rheumatoid arthritis and controls. e First two principal components of the usage of V-J segments pairs (N = 4054 variables from the seven immune receptor chains) in rheumatoid arthritis and controls. Abbreviations: P, p-value; PC, principal component

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Genome Biology

ISSN: 1474-760X

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