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Fig. 5 | Genome Biology

Fig. 5

From: L-GIREMI uncovers RNA editing sites in long-read RNA-seq

Fig. 5

Long-read RNA-seq detected highly structured regions. a IGV plot for an example where many reads had internal skipping. This region harbors two Alus. The double-strand RNA structure predicted by RNAfold is shown. b Diagram illustrating RT-induced template switching that may induce region-skipping in long reads. c Read coverage of predicted dsRNAs with or without region-skipping patterns. d Histogram of dsRNAs with different fractions of reads that showed region-skipping patterns. e The length of skipped regions within predicted dsRNAs (median = 813, 627 for the AD and GM12878 data, respectively)

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