Genetic impacts on DNA methylation help elucidate regulatory genomic processes

Table 1 Summary characteristics for the five UK cohort sample sets

Cohort^a	Sample size	Percentage females	Percentage smokers	Median age [range]
TwinsUK	394	100	5.6	64.5 [42.4, 86.6]
1946BC-99	1348	52.3	24.2	53.4 [53, 54]
1946BC-09	197	59.4	11.2	63.2 [60.3, 64.6]
1958BC-1	183	50.8	21.3	45.1 [44.5, 45.8]
1958BC-2	236	54.2	42.4	45.1 [44.3, 46.0]
Total	2358	60.9	21.5	53.5 [42.4, 86.6]

^a1946BC-99 and 1946BC-09 refer to independent samples from the 1946 birth cohort collected at two different time points and stratified to facilitate data handling. 1958BC-1 and 1958BC-2 refer to samples from the 1958 birth cohort processed in two different batches (see the ‘Methods’ section for further details)

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