Fig. 3
From: Genetic impacts on DNA methylation help elucidate regulatory genomic processes
DNA methylation quantitative trait loci (meQTLs) for CpG sites genome-wide. Association analysis carried out between 724,499 CpGs vs. 6,361,063 SNPs. a Genomic distribution of meQTL associations at a significance level of FDR \(< 0.05\). The x-axis corresponds to the position of the SNPs within the 22 chromosomes and the y-axis to the position of the CpGs, with each pixel binning a range of 25 Mbps. The colour scale indicates the number of associations between specific CpGs/SNPs locations, on a logarithmic scale. b Histogram of distances between the CpGs and their most significant cis-meQTL SNPs. c Bar plot of absolute distances between the CpGs and their most significant trans-meQTL SNPs. Intra-chromosomal associations are shown in purple, and inter-chromosomal in grey