Table 3 Pearson’s R correlation coefficients between CDS wild type activity and SIFT, PolyPhen, and REVEL predictor scores. CDS, coding sequence
| Â | CDS mean percent of wild-type activity | SIFT scores | PolyPhen scores | REVEL scores |
|---|---|---|---|---|
CDS mean percent of wild-type activity | 1 | 0.44 |  − 0.56 |  − 0.51 |
SIFT scores | 0.44 | 1 |  − 0.67 |  − 0.64 |
PolyPhen scores |  − 0.56 |  − 0.67 | 1 | 0.86 |
REVEL scores |  − 0.51 |  − 0.64 | 0.86 | 1 |