Fig. 6

Protein-RPF concordance is linked to the initial protein abundance and the protein half-life. A Bar plots showing the percentages of proteins that showed high (R > 0.5), medium (R > 0.2 and R < 0.5), or low (R < 0.2) correlation (Spearman) with RPF for “All” proteins (n = 4,108) and different protein groups in Fig. 3A. B Box plots showing the protein-RPF correlation based on the protein abundance in FGOs. C Box plots showing half-lives determined in mouse embryo neuron [37] or embryonic fibroblast cell line NIH3T3 [36] for different protein groups. D Box plots showing protein half-lives for different protein-RPF correlation groups. The significance for all plots was calculated by Wilcoxon rank-sum test (two-tailed). ***, P-value < 0.001; **, P-value < 0.01; ns, non-significant