Fig. 7
From: Synergising single-cell resolution and 4sU labelling boosts inference of transcriptional bursting
a Heatmap showing the Spearman’s rank rho as the heat intensity value for the correlations between bursting parameter estimates and the mean promoter-localised HM coverage values across the -2000:5% and 5%:100% regions. More intense red or blue colouration indicates a stronger positive or negative correlation, respectively, while neutral indicates no/weak correlation. b Heatmap showing the Spearman’s rank p-value (adjusted for multiple hypothesis testing) as the heat intensity value for the correlations between bursting parameter estimates and the mean promoter-localised HM coverage values across the -2000:5% and 5%:100% regions. The heat values are discretised, corresponding to negative log10 p-value thresholds. For example, the most intense blue indicates that, for the given correlation, \(10^{-2}<p\), meaning no statistical significance, the neutral colour indicates that \(10^{-4}<p\le 10^{-3}\), while the most intense red indicates that \(p\le 10^{-6}\)