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Fig. 4 | Genome Biology

Fig. 4

From: MORC proteins regulate transcription factor binding by mediating chromatin compaction in active chromatin regions

Fig. 4

MORC proteins influence TF binding through chromatin compaction. a Metaplot and heatmap showing chromatin accessibility changes in MORC7A-unique, MORC7B-unique, MORC7-Pol V Common, and Pol V-unique regions profiled by ATAC-seq. b A representative screenshot showing higher chromatin accessibility at the promoter of SAUR6 in the morchex mutant. c Volcano plot showing changes in TF footprints in MORC7A regions, comparing morchex and wild type. d Volcano plot showing changes in TF footprints in MORC7B regions, comparing morchex and wild type. e Volcano plot showing changes in TF footprints in MORC7-Pol V Common regions, comparing morchex and wild type. f Volcano plot showing changes in TF footprints at Pol V-unique regions, comparing morchex and wild type. g Metaplot showing TF footprint changes for MORC7A-unique regions in the morc4morc7 mutant. h Metaplot showing TF footprint changes for MORC7A-unique regions in the morc6 mutant. i Metaplot showing TF footprint changes for MORC7A-unique regions in the morchex mutant. j Volcano plot showing TF changes for ZF off-target sites, comparing ZF-MORC6 and fwa-4 plants. P values were calculated by the two-sided Student’s t-test

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