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Fig. 1 | Genome Biology

Fig. 1

From: YY1 lactylation in microglia promotes angiogenesis through transcription activation-mediated upregulation of FGF2

Fig. 1

Retinal microglia are essential for retinal neovascularization. a OIR modeling flow chart. b Iba-1 (microglial marker) and CD31 (endothelial cell marker) double-stained confocal images of retinas in normoxia control (Normal P17) and OIR mice (OIR P17). c PLX3397 dosing flow chart. d Iba-1 and CD31 double-stained retinal flat mounts (OIR (DMSO) and OIR (PLX3397)). The number of Iba1 positive cells was recorded and analyzed by CellSens Dimension software (n = 5 mice per group). Scale bars, 1000 μm (upper panel of b and top left panel of d) or 50 μm (lower panel of b and bottom right panel of d). **p < 0.01

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Genome Biology

ISSN: 1474-760X

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