Fig. 6

Comparison of HOR annotations between HiCAT and HORmon. a Compared with HORmon in annotation coverage. b Compared with HORmon in annotation continuity. p-value = 4.6e − 7. *** represents p-value < 0.001, Wilcoxon rank sum test. c Monomer Sankey plot for CEN9 showing the high consistency between the two methods. To display the frequent monomers, we filtered the links with fewer than 10 matches. The complete Sankey plots are shown in Additional file 1: Fig. S7g-i. d–f Structure and annotation of CEN9 (d), CEN13 (e), and CEN18 (f) with two methods. Here, “canonical” represents canonical HORs, “partial” represents partial HORs, and “monomers” represents monomers that do not belong to any HORs. g The number of monomer patterns in CEN18 R1L12. D9Z4, D13Z1, and D18Z1 are previously reported HORs. MP is the monomer pattern. # means the number of