Fig. 3
From: Multi-omics analysis identifies drivers of protein phosphorylation
pQTL and phQTL mapping from CC strains in heart, kidney, and liver tissues. Stringently detected (FDR < 0.1) A pQTL, B phQTL, and adjusted phQTL in heart (left), liver (middle), and kidney (right) tissues. QTL are plotted by the genomic positions of proteins against QTL coordinates. Adjusted phQTL were highlighted in black. C Adjusted phQTL identified on EIF3B pS90 co-mapped in all three tissues. Relative abundances (batch corrected log2 intensity) of EIF3B pS90 in each tissue were grouped based on founder local haplotypes. D LOD scores of local and distant phQTL (FDR < 0.1 or 0.5) changed after adjusting for their parent protein abundances in heart, kidney, and liver tissues. MCAT pS41, GAS2 pS283, and COMT pS261 were labelled