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Fig. 4 | Genome Biology

Fig. 4

From: The Network Zoo: a multilingual package for the inference and analysis of gene regulatory networks

Fig. 4

Multi-tiered CCLE map links genotype to cellular phenotypes. A Screenshot of the online resource accessible at https://grand.networkmedicine.org/cclemap/ that uses DRAGON to link promoter methylation (orange triangle), copy number variation (pink diamond), histone marks, miRNA levels, gene expression (blue circle), protein levels (purple circle), metabolite levels (green square), drug sensitivity, and cell fitness following CRISPR gene knockout. Green arrows indicate positive partial correlation and red arrows indicate negative partial correlation. B Positive partial correlations between copy number variation and gene expression of CDKN2A and CDKN2B. C Negative partial correlation between MIR378D1 levels and TBC1D21 expression

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