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Fig. 5 | Genome Biology

Fig. 5

From: SampleQC: robust multivariate, multi-cell type, multi-sample quality control for single-cell data

Fig. 5

QC method comparisons on complex biological data. A Biaxial empirical density plot of QC metrics for single nuclei data, showing one selected sample, annotated with models fit by SampleQC. Color indicates density of cells with the same QC metrics. B Mahalanobis distances to nearest cluster under fit SampleQC model, with large values indicating low likelihood under multivariate Gaussian mixture model. C, D, and E Outliers detected by SampleQC, scater, and miQC, respectively. SampleQC outliers include user specification that QC cell types with mean splice ratio \(>3\) should be excluded

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