Skip to main content
Fig. 4 | Genome Biology

Fig. 4

From: β-actin mediated H3K27ac changes demonstrate the link between compartment switching and enhancer-dependent transcriptional regulation

Fig. 4

Transcriptional changes in compartment switching regions correlate with gain or loss of enhancers. Volcano plots showing the RNA-Seq expression and FDR of all genes overlapping switching (A to B or B to A) regions for (i) β-actin KOvsWT, (ii) KO-actin vs β-actin KO (note: log2FC and FDR for KO-actin vs KO comparison is shown for genes classified as switching in KOvsWT comparison), and (iii) ESCvsMEF. Red and blue fill represents genes gaining and losing enhancers upon compartment switching while grey fill represents zero net change in enhancers. p-values based on two-tailed Wald test corrected for multiple testing using Benjamini–Hochberg procedure

Back to article page

Genome Biology

ISSN: 1474-760X

Contact us