Fig. 6
From: Auxin-inducible degron 2 system deciphers functions of CTCF domains in transcriptional regulation
ZF1 and ZF10 differential peaks enriched for specific CTCF binding motifs. a Heatmap of motif analysis of CTCFAID2/dZF1 decreased peaks identifying conserved DNA signatures including a G (red arrow) positioned 4Â bp proximal from the 20-bp consensus sequence motif [46]. b Heatmap of motif analysis of CTCFAID2/dZF1 control peaks showing no enrichment of downstream DNA signatures. c Heatmap of motif analysis of CTCFAID2/dZF10 decreased peaks identifying conserved DNA signatures (red arrow) positioned upstream from the 20-bp consensus sequence motif. d Heatmap of motif analysis of CTCFAID2/dZF10 control peaks showing no enrichment of upstream DNA signatures. For all, green, blue, yellow, and red indicated A, C, G, and T bases, respectively. The right panel shows the motif consensus logo in information bits for five clusters assigned by unsupervised hierarchical clustering using hamming distance