Fig. 6

Distribution of proportions of genes highly expressed in one stage of cerebral development. Four series of proportions are shown: all genes and PSGs with biased expression in one stage, genes positively selected on coding and promoter regions. PCW, M, and Y refer to postconceptional weeks, months, and years, respectively. For each stage, we implemented binomial tests and examined whether PSGs and positively selected genes showed significant excess or depletion relative to the genomic background. Only four stages showed at least one significant (FDR < 0.1) test result and the top four GO terms for these stages are shown. For 19–24 PCW, no significant terms were identified