Fig. 4

The inter-chromosomal translocation event for fusion gene EIF3K–CYP39A1 detected and validated by multiple technologies. a CYP39A1 gene on chromosome 6 is translocated and inverted to make a fusion transcript with EIF3K gene on chromosome 19. The fusion transcript was detected from RNA-seq data. b EIF3K–CYP39A1 translocation and inversion event detected from Bionano optical mapping. The blue bar in the middle denotes the reference genome, the green bars denote the optical mappings and the vertical lines between the blue and green bars represent the mapping between reference and maps. Top green bar shows maps on chromosome 6 and the bottom green bar shows maps on chromosome 19. c EIF3K–CYP39A1 translocation and inversion event are detected from NGS technologies from Illumina (top), PacBio (middle), and 10X Genomics linked reads (bottom). The visualization is generated using SVVIZ