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Fig. 5 | Genome Biology

Fig. 5

From: Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3′ untranslated region

Fig. 5

Impact of the engineered T-to-C substitution on mouse adiposity. A Body weight of 11–15-week-old Fnip2T/T (n=12) and Fnip2C/C (n=13) females and 10–13-week-old Fnip2T/T (n=19) and Fnip2C/C (n=21) males. B Correlation between Fnip2 mRNA levels in livers from Fnip2T/T (n=14) and Fnip2C/C (n=15) mice and their body weight. C Fat content was obtained by measuring body composition in 5–6-week-old Fnip2T/T (n=5) and Fnip2C/C (n=6) females and Fnip2T/T (n=8) and Fnip2C/C (n=9) males. D Fat content was obtained by measuring body composition in 11–15-week-old Fnip2T/T (n=8) and Fnip2C/C (n=9) females and 10–13-week-old Fnip2T/T (n=9) and Fnip2C/C (n=9) males. In all cases, statistical significance was calculated using an unpaired two-tailed t-test

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Genome Biology

ISSN: 1474-760X

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