Fig. 3

Evaluation using simulated datasets. a The schematic illustration of data simulation procedure. The long box indicates the LR pair between two cell types, where its face color represents interaction type and edge color represents expression state. The rounded rectangles indicate cell types and edge color represents distance type between cell types. b The DES ranks of CCI tools evaluating using 15 simulated datasets. Tools are sorted by the median DES. c The F1 ranks of CCI tools evaluating using 15 simulated datasets. Using simulated interactions as the positive set. Tools are sorted by the median F1 score