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Fig. 4 | Genome Biology

Fig. 4

From: Prediction of evolutionary constraint by genomic annotations improves functional prioritization of genomic variants in maize

Fig. 4

Relationship between phylogenetic nucleotide conservation (PNC) and experimental annotations at SNPs. A Decrease in observed and predicted PNC over within-species variability, quantified by MAF in reference panel Hapmap 3.2.1 [15]. B Increase in predicted PNC in accessible chromatin regions, defined by MNase hypersensitivity in shoot or root tissues [21]. C Positive association between observed PNC and expression QTL effect (in absolute values) in shoot or root tissues, estimated in a diverse maize panel [22]

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Genome Biology

ISSN: 1474-760X

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