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Fig. 7 | Genome Biology

Fig. 7

From: Single-cell diploid Hi-C reveals the role of spatial aggregations in complex rearrangements and KMT2A fusions in leukemia

Fig. 7

The CRGs may be involved in the RUNX1-mediated transcription factories. A The distributions of KMT2A partners, CR genes (CRGs), and control genes in different transcriptional sub-compartments. B CRGs are close to the nuclear center than control genes (Wilcoxon rank-sum test). C Co-expressions clusters among CRGs. D Enrichments of CRGs in the targets of TFs based on three different databases. E Intersections of enriched TFs among the three databases. F The distribution (density plot) of the distance changes for colocalized CRG pairs before and after RUNX1 knockdown

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Genome Biology

ISSN: 1474-760X

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