Fig. 5

Significant enriched GO pathways by DMG and DEG analysis in epi-lines. a Enriched GO pathways shared by the four epi-lines in Arabidopsis as well as by F1 hybrid DMGs from the C24 x Ler cross by our analysis. Original methylation data for the F1 hybrid were previously reported [22]. Heat map was generated using the fold enrichment of GO terms (FDR < 0.05) common between all four epi-lines. Blue arrows indicate pathways likely contributing to epigenetic change and red arrows indicate pathways likely associated with plant developmental changes. Complete list of GO terms is available in  Extended Data 2 and 3. b Enriched GO pathways from DEGs (FDR<0.05) shared by Epi 8 and Epi 24 floral stem tissues. Heat map displays the fold enrichment of GO terms (FDR < 0.05) common between both the epi-lines. Complete list of GO terms is available in Extended Data 4. DAVID GO (version 6.8) [23] was used for GO enrichment analysis. GO terms with EASE score (a modified Fisher exact P-value) < 0.05 were used for FDR calculation. FDR was calculated using package stats (version 3.6.0; p.adjust method = FDR) in R. Package ggplot2 (version 3.3.3) in R was used to generate heatmap