Fig. 2From: High-throughput techniques enable advances in the roles of DNA and RNA secondary structures in transcriptional and post-transcriptional gene regulationSchematic overview of Non-B DNA enrichment relative to gene features. Higher density of non-B DNA structures is observed at promoter regions, 5’UTRs, regions flanking splice sites and at the 3’UTR. Formation of secondary structures is also facilitated by negative supercoiling and at actively transcribed regions relative to the direction of the transcribing RNA polymerase [2, 3]Back to article page