Fig. 2

Concordant taxa accumulations across genera, confounded differential richness inference, and the Prokounter strategy. A Sample-wide taxa accumulations are visualized with respect to sample depth (left). Within-genus taxa accumulations are visualized with respect to the total recovered genus abundances for two gener a, i.e., the sum of the abundances of all taxa within the genus. B Differential richness log-fold changes (LFC, y-axis) track differential relative abundance fold changes (LFC, x-axis) in the waste-water treatment survey. C Prokounter exploits within-genus accumulation data to model false taxa accumulation rates. When exploited in a standard Poisson regression setting, the resulting differential richness fold changes are uncorrelated with genus-wide differential abundance statistics (right). Dashed lines represent confidence intervals. Points colored in red are the genus-specific differential richness inferences for the waste-water treatment survey