Fig. 3

cfNano preserves nucleosome positioning signal. A Alignments to 9780 CTCF motifs within non-promoter ChIP-seq peaks were taken from [34]. B Sequence coverage of mononucleosomes (130–155 bp) from cfNano samples is shown as fold change vs. average coverage across the genome (top). Mononucleosome coverage for matched Illumina samples (bottom). C The same analysis, using a randomly selected downsampling of 2 million reads from each sample. Two cfNano samples with less than 2M reads total are omitted