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Fig. 4 | Genome Biology

Fig. 4

From: scDART: integrating unmatched scRNA-seq and scATAC-seq data and learning cross-modality relationship simultaneously

Fig. 4

The results of scDART and baseline methods on the human hematopoiesis dataset. a Latent embedding of scDART, Liger, Seurat, and UnionCom. Cells are colored with cell type annotations from the original paper. Red lines show the inferred trajectory backbone. All plots share the same legend as in the Liger plot. b Latent embedding of scDART, Seurat, Liger, and UnionCom. Cells colored with data batches. All plots share the same legend as in the UnionCom plot. c The expression level of STMN1 and GAPDH along MEP lineage, and SATB1 and RUNX2 along CLP lineage. Cells are ordered on the x-axis according to the inferred pseudotime. d The deviation values (from ChromVAR) of differentially accessible motifs along MEP and CLP lineages. The black and red lines in (c) and (d) correspond to the fitted statistical models under alternative and null hypothesis, respectively, when conducting likelihood ratio test

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Genome Biology

ISSN: 1474-760X

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