Fig. 5
From: Comprehensive assessment of differential ChIP-seq tools guides optimal algorithm selection
Influence of FRiP on the performance of DCS tools. a AUPRCs of the top 11 DCS tools (based on AUPRC for the initial six shape and regulation scenarios) depend on the background noise. Boxplots per DCS tool are ordered by noise level, from high to low. b FRiP in the sub-sampled datasets. Darker color represents higher FRiP. Top panel, TFs; middle panel, sharp marks; bottom panel, broad marks. Whiskers indicate the standard deviation. c AUPRCs for sub-sampled ChIP-seq data from different TFs and histone marks depend on FRiP. Boxplots per DCS tool are ordered by FRiP from low to high. Top panels, TFs; middle panels, sharp marks; bottom panels, broad marks. Box plot limits, 25% and 75% quantiles; center line, median; whiskers, 1.5× interquartile range