Fig. 3
From: Comprehensive assessment of differential ChIP-seq tools guides optimal algorithm selection
Performance of benchmarked DCS tools based on AUPRC values. a Overview of AUPRC values per DCS tool for all test scenarios compared to random regions (see “Methods”), ranked by median AUPRC. Box plot limits, 25% and 75% quantiles; center line, median; whiskers, 1.5× interquartile range. b Density plots of AUPRC values per scenario for TFs (left), sharp (middle), and broad marks (right). The two (one for each regulation scenario) top-performing parameter sets per DCS tool are highlighted as colored symbols, remaining data points are visualized as density clouds. c AUPRC values of the top five DCS tools parameter sets per scenario (TF left, sharp mark middle, and broad mark right column; 50:50 regulation scenario top and 100:0 bottom row). Colored boxes indicate peak caller, if applicable and if default or adjusted parameter setups were used; whiskers, standard error of the mean