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Fig. 6 | Genome Biology

Fig. 6

From: Refining colorectal cancer classification and clinical stratification through a single-cell atlas

Fig. 6

Continuous subtype scoring across cell type (GSE39582 [45], GSE1736 [48]). A, B Continuous scores reported by CMS classification across cell types show minimal separation in the top 2 principal components in GSE39582 and GSE17536 datasets respectively. All cell types are represented in CMS1-4 using PCSS1 and PCSS2 scores. Note that the cell types largely form a continuum along CMS status and are not clustered in discrete subtypes separate from one another. Cells and markers are colored by bulk CMS status accordingly to the tumor sample of origin. (PCSS1 = PC Cluster Subtype Scores1, PCSS2 = PC Cluster Subtype Scores1)

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