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Fig. 2 | Genome Biology

Fig. 2

From: One Cell At a Time (OCAT): a unified framework to integrate and analyze single-cell RNA-seq data

Fig. 2

Integrating multiple scRNA-seq datasets with OCAT. A UMAP projection of five integrated human pancreatic scRNA-seq datasets from heterogeneous sequencing platforms by OCAT, Seurat v3, Harmony, and Scanorama. The top panel is colored by the annotated cell types, and the bottom panel is colored by the dataset. B UMAP projection of two integrated human dendritic datasets with non-overlapping cell types by OCAT, Seurat v3, Harmony, and Scanorama. The top panel is colored by the annotated cell types, and the bottom panel is colored by the dataset. C UMAP projection of two integrated PBMC scRNA-seq datasets by OCAT (see Additional file 3: Fig. S1 for a full comparison with Seurat v3, Harmony, and Scanorama). D Memory usage and runtime of OCAT, Seurat v3, Harmony, and Scanorama on five scRNA-seq integration tasks

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